Gastrointestinal and hepatobiliary disorders

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Gastrointestinal and hepatobiliary disorders

Pharmacotherapy for gastrointestinal and hepatobiliary disorders

we will be looking at the pharmacologic management of gastrointestinal and hepatobiliary disorders, including:  hepatitis C, cirrhosis, nausea/vomiting, GERD, PUD, constipation, diarrhea, irritable bowel syndrome, & inflammatory bowel disease.

For the Assignment this week, you will evaluate and determine a diagnosis for the case study patient who presents with symptoms of a possible GI/hepatobiliary disorder.  You will then justify your diagnosis, including your rationale for the diagnosis.  Based upon your diagnosis, you will then determine an appropriate treatment plan for the case patient.  For full credit, please ensure that you provide the appropriate doseroute and frequency of administration of the medication(s) prescribed.  Approach this as if you are writing a prescription for your patient – what drug, dose, route and frequency would you prescribe?

When writing your Week 4 Assignment, consider the following scenario:

DC is a 46-year-old female who presents with a 24-hour history of RUQ pain.  She states the pain started about 1 hour after a large dinner she had with her family.  She has had nausea and one instance of vomiting before presentation.



Type II DM


DVT – Caused by oral BCPs



Temp: 98.8°F

Wt: 202 lbs

Ht: 5’8”

BP: 136/82

HR: 82 bpm

Current Medications:

Lisinopril 10 mg daily

HCTZ 25 mg daily

Allopurinol 100 mg daily

Multivitamin daily


Notable Labs:

WBC: 13,000/mm3

Total bilirubin: 0.8 mg/dL

Direct bilirubin: 0.6 mg/dL

Alk Phos: 100 U/L

AST: 45 U/L

ALT: 30 U/L







Eyes: EOMI

HENT: Normal

GI: Nondistended, minimal tenderness

Skin: Warm and dry

Neuro: Alert and Oriented

Psych: Appropriate mood

Write a 1-page paper that addresses the following:

  • Explain your diagnosis for the patient, including your rationale for the diagnosis.
  • Describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
  • Justify why you would recommend this drug therapy plan for this patient. Be specific and provide examples.

References x 3 to include:

Chalasani, N., Younossi, Z., Lavine, J. E., Charlton, M., Cusi, K., Rinella, M., . . . Sanya, A. J. (2018). The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases Links to an external site.Hepatology, 67(1), 328–357. Retrieved from